Sermorelin (GRF 1-29) Peptide | >99% Purity Research Grade

Sermorelin, also known as GRF 1-29, is a synthetic peptide fragment of Growth Hormone-Releasing Hormone (GHRH). This precisely engineered peptide contains the first 29 amino acids crucial for stimulating pituitary receptors. Peptides Skin is a trusted B2B research peptide supplier, providing Sermorelin exclusively for in-vitro laboratory research.

Every Sermorelin vial supplied by Peptides Skin undergoes rigorous HPLC and Mass Spectrometry testing, ensuring >99% purity, consistency, and stability essential for reliable scientific studies.

Product Overview & Key Features

Sermorelin is a vital tool in scientific research focused on growth hormone regulation and endocrine signaling. Its 29-amino acid sequence is designed to maintain full biological receptor activity within the anterior pituitary, making it highly effective for targeted studies.

• Purity: Over 99%, verified by HPLC-testing
• Form: Lyophilized white powder for optimal stability
• Origin: Synthetically produced, ensuring contaminant-free research material
• Category: Research peptides – strictly for laboratory use only

Technical Specifications

Mechanism of Action

In controlled research settings, Sermorelin functions as a potent GHRH agonist. It selectively binds to GHRH receptors on somatotroph cells, initiating a cAMP-dependent signaling pathway. This activation leads to increased transcription of growth hormone and promotes its natural, pulsatile release.

This characteristic pulsatile stimulation makes Sermorelin invaluable for studying complex endocrine rhythms and intricate growth hormone feedback loops within biological systems.

Research Applications

Metabolic Research Applications

Studies utilizing Sermorelin often investigate how GHRH analogs influence critical metabolic processes such as lipolysis, protein turnover, and overall cellular metabolism.

Sleep & Circadian Rhythm Studies with Sermorelin

Researchers employ Sermorelin to analyze the precise relationship between endogenous growth hormone pulses and various sleep cycles, particularly slow-wave sleep.

Neuroendocrine Research & Sermorelin

Exploratory research uses GHRH analogs like Sermorelin to investigate potential neuroprotective or cognitive effects in various animal models, contributing to a deeper understanding of neuroendocrine interactions.

Storage & Handling Guidelines

• Lyophilized State: Store at -20°C for long-term stability (up to 24 months).
• Reconstituted State: Store at 4°C and use within 2–3 weeks to maintain efficacy.
• Important Note: Avoid repeated freeze–thaw cycles to preserve peptide integrity.

Safety & Compliance

For Research Use Only. This product is not intended for human consumption, medical, veterinary, or diagnostic applications. Purchase is strictly restricted to qualified researchers and laboratories adhering to ethical research practices.

Why Choose Peptides Skin for Your Research?

• Guaranteed High Purity: All peptides come with batch traceability and third-party testing verification.
• Reliable Logistics: Fast, temperature-controlled shipping ensures product integrity upon arrival.
• Expert Support: Access to professional research support for any inquiries.
• Commitment to Quality: Dedicated to supplying only the highest quality research-grade peptides.

Sermorelin FAQ

What is Sermorelin used for in research?

Sermorelin is primarily used to study pituitary stimulation, growth hormone release, and essential metabolic signaling pathways.

How does Sermorelin differ from HGH?

Sermorelin stimulates natural GH secretion, while HGH provides external GH. They are often compared in endocrine feedback studies.

How long does reconstituted Sermorelin remain stable?

Reconstituted Sermorelin stays stable for approximately 14–21 days when stored correctly at 4°C.

Is Sermorelin legal to purchase for research?

Yes, Sermorelin is legal to purchase for laboratory research and education. It is not approved for human consumption or therapeutic use.