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Vial labeled 'Melanotan 1' with 'Peptides Skin' branding on a white background

Melanotan 2

$49.00 USD

High-purity synthetic alpha-MSH analog designed strictly for in-vitro and laboratory research applications.

Product Overview

Melanotan 2 (commonly abbreviated as MT-2) is a synthetic cyclic heptapeptide and an analog of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). It is widely utilized in scientific research to investigate the physiological mechanisms of melanogenesis, energy homeostasis, and sexual arousal pathways in animal models.

As a specialized B2B supplier of research peptides, Peptides Skin provides Melanotan 2 in a lyophilized powder form, ensuring maximum stability and shelf life for laboratory use. This product is strictly intended for laboratory research and development purposes and is not approved for human consumption, cosmetic use, or therapeutic administration.

Technical Specifications

Product Name Melanotan 2 (MT-II)
Sequence Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-NH2
CAS Number 121062-08-6
Molecular Formula C50H69N15O9
Molar Mass 1024.18 g/mol
Purity ≥ 99.0% (determined by HPLC)
Form Lyophilized White Powder

Key Features of Melanotan 2

  • High Receptor Affinity: Melanotan 2 acts as a non-selective agonist for melanocortin receptors, specifically MC1R, MC3R, MC4R, and MC5R.
  • Enhanced Stability: The cyclic lactam structure protects the peptide from rapid enzymatic degradation, offering a longer half-life in research environments compared to linear alpha-MSH.
  • Research Grade Purity: Every batch undergoes rigorous quality control, including High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS), to ensure purity exceeds 99%.

Research Applications & Mechanism of Action

Melanotan 2 is a primary subject of study in several biological fields. It is categorized as a research chemical and is utilized to explore specific receptor signaling pathways.

Melanogenesis and Pigmentation

The peptide is extensively used to study the stimulation of melanocytes via the MC1 receptor. Research focuses on how Melanotan 2 influences the production of melanin pigments (eumelanin) without the requirement of UV radiation exposure. This makes it a critical tool in studying photoprotection mechanisms and potential interventions for light-sensitivity disorders in animal models.

Metabolic and CNS Research

By binding to MC3 and MC4 receptors in the central nervous system, Melanotan 2 allows researchers to investigate pathways involved in appetite suppression, energy expenditure, and lipid metabolism. Furthermore, it is used in studies regarding sexual function and arousal to understand the neurological basis of erectile function and libido in test subjects.

Storage and Handling Guidelines

To maintain the integrity of the peptide, proper storage conditions are essential:

  • Lyophilized (Powder): Store at -20°C. Stable for up to 24 months.
  • Reconstituted (Liquid): Once mixed with bacteriostatic water or a sterile solvent, the solution should be stored at 4°C and used within 2-4 weeks. Avoid repeated freeze-thaw cycles.
  • Handling: Use sterile techniques. Solubilization should be performed gently; do not shake vigorously to avoid damaging the peptide structure.

Safety & Compliance (Research Use Only)

Warning: The products offered by Peptides Skin, including Melanotan 2, are intended exclusively for in-vitro laboratory research and development. They are NOT for human use, diagnostic, or therapeutic procedures.

Researchers must handle this compound in a laboratory setting, adhering to standard safety protocols. Improper use, including introduction into humans or animals outside of approved clinical trials, is strictly prohibited. Consult our full research peptide catalog for safety data sheets (SDS) and technical documentation.

Why Choose Peptides Skin?

When conducting sensitive experiments, the consistency of your reagents is paramount. Peptides Skin is a trusted partner for laboratories worldwide.

  • Verified Purity: We provide transparent access to HPLC and MS reports for every batch.
  • Reliable Logistics: Secure shipping ensures peptides arrive in optimal condition.
  • Expert Support: Our team understands the nuances of peptide research and is available to assist with technical queries.

Frequently Asked Questions

Is Melanotan 2 stable at room temperature?

In its lyophilized powder form, Melanotan 2 is stable at room temperature for short periods (during shipping), but for long-term storage, it should be kept at -20°C. Once reconstituted, it must be refrigerated.

What is the solubility of Melanotan 2?

Melanotan 2 is soluble in water and saline. Researchers typically use sterile bacteriostatic water for reconstitution in laboratory settings.

Does Melanotan 2 affect skin color in research subjects?

Studies indicate that Melanotan 2 stimulates melanocytes to produce melanin, which can result in increased pigmentation in animal test subjects.