PT-141
PT-141 Peptide (Bremelanotide) — Research Use Only (RUO) Overview
PT-141, commonly referenced as bremelanotide peptide, is a synthetic melanocortin receptor agonist used in controlled research workflows to investigate receptor-mediated signaling and downstream pathway readouts in non-clinical models. This page provides laboratory context only and does not imply clinical outcomes.
PT-141 (Bremelanotide) Specifications — CAS 189691-06-3, ≥99% HPLC
| Product Name | PT-141 (Bremelanotide) |
|---|---|
| CAS Number | 189691-06-3 |
| Molecular Formula | C50H68N14O10 |
| Molecular Weight | ~1025.2 g/mol |
| Peptide Type | Cyclic melanocortin receptor research peptide |
| Purity | ≥99% (HPLC verified) |
| Verification | HPLC / MS tested (batch-based) |
| Physical Form | Lyophilized powder |
| Documentation | CoA available upon request |
| Grade | Research Use Only (RUO) |
PT-141 Keywords Embedded for Search Intent (USA)
Common queries include pt-141 peptide, bremelanotide, pt-141 bremelanotide, melanocortin receptor agonist, MC4R, MC3R, pt-141 lyophilized powder, pt-141 storage, and pt-141 reconstitution.
Below, those terms are addressed naturally through RUO-safe technical sections and FAQs (no medical claims).
What Is PT-141 (Bremelanotide)? Melanocortin Receptor Research Peptide
In research literature, bremelanotide (PT-141) is discussed as a melanocortin-pathway probe, often evaluated for activity across melanocortin receptor subtypes (commonly referenced in CNS signaling models). Researchers use PT-141 to explore receptor binding, cAMP signaling, and pathway-level modulation under defined experimental conditions.
PT-141 Mechanism of Action in MC4R / MC3R Signaling Models (Research Context)
PT-141 is widely referenced for melanocortin receptor pathway investigation, supporting assays that quantify receptor activation and downstream signaling readouts (e.g., cAMP-linked responses) in controlled in-vitro systems. Experimental design, receptor subtype selection, and endpoints are protocol-dependent.
PT-141 Research Applications: Receptor Binding, CNS Pathways, and Autonomic Readouts
- Melanocortin receptor binding assays: receptor affinity/activation profiling in cell systems
- MC4R pathway mapping: downstream signaling cascade exploration in mechanistic workflows
- Neuroscience models: CNS-linked pathway studies focused on signaling and regulatory circuits
- Comparative peptide research: contrast vs. other melanocortin-pathway peptides (protocol-dependent)
- Analytical/QC workflows: identity/purity checks and reproducibility tracking in lab environments
PT-141 Storage and Handling: Lyophilized Peptide Powder + Reconstitution (RUO)
For pt-141 storage and preparation in RUO workflows, follow your laboratory SOP and the product documentation. Many labs store lyophilized peptides cold, protected from light and moisture, and prepare solutions only as needed for assays.
- Lyophilized PT-141: store at −20°C or below, protected from light/moisture
- After preparation: use within your protocol stability window (solvent/time are assay-dependent)
- Best practice: aliquot where appropriate; avoid repeated freeze–thaw cycles
Why Researchers Choose Peptides Skin for PT-141 (Bremelanotide) RUO Supply
- Verified purity: ≥99% HPLC verified (batch-based)
- Identity support: MS testing and traceability practices
- CoA availability: documentation for qualified research buyers
- Secure shipping: packaging optimized for stability during transit
FAQs — PT-141 Peptide (Bremelanotide) Research Use Only
What is PT-141 peptide (bremelanotide) in research?
PT-141 (bremelanotide) is a melanocortin-pathway research peptide used in non-clinical workflows to study receptor signaling (e.g., MC4R/MC3R) and downstream mechanistic readouts in controlled systems.
Is PT-141 from Peptides Skin approved for human use?
No. Peptides Skin supplies PT-141 strictly as Research Use Only (RUO). It is not intended or approved for human or veterinary use, injection, or consumption.
What are the CAS number and molecular weight of PT-141?
Common references list CAS 189691-06-3 and a molecular weight of approximately ~1025.2 g/mol for bremelanotide (PT-141). Always verify against batch documentation for your laboratory records.
How should PT-141 lyophilized powder be stored?
Store lyophilized PT-141 at −20°C or below, protected from light and moisture. Follow your SOP and minimize freeze–thaw cycles to reduce experimental variability.
Do you provide PT-141 CoA and HPLC/MS data?
Yes. CoA is available upon request, with batch-based HPLC purity verification and MS identity support for qualified research customers.
For laboratory research and development purposes only. Not for human or veterinary use, injection, or consumption. Not intended to diagnose, treat, cure, or prevent any disease. Any mention of mechanisms refers exclusively to controlled research models.