Semaglutide

Semaglutide (SEMA) is a high-purity, synthetic glucagon-like peptide-1 (GLP-1) receptor agonist, supplied for laboratory and research purposes. As an analog of human GLP-1, it is a primary compound for in-vitro studies related to glycemic control, appetite regulation, and metabolic pathways.

At Peptides Skin, we provide lyophilized Semaglutide with a verified purity of ≥99%, ensuring your experimental results are based on a reliable and consistent compound. This product is intended strictly for scientific investigation.

Semaglutide for Research: An Overview

Semaglutide is a modified peptide engineered for enhanced stability and a longer half-life compared to native GLP-1. This makes it an invaluable tool for researchers needing to observe sustained GLP-1 receptor activation in controlled laboratory models.

Is Semaglutide a Peptide?

Yes, Semaglutide is a synthetic peptide composed of a chain of amino acids. Its structure is based on the endogenous hormone GLP-1, with specific modifications to resist enzymatic degradation, making it ideal for research applications requiring long-acting effects.

Semaglutide vs. Tirzepatide: Key Differences for Researchers

A frequent question is how Semaglutide compares to Tirzepatide. While both are used in metabolic research, they function differently:

• Semaglutide: A single-agonist that targets the GLP-1 receptor. Its research focus is primarily on glycemic control and appetite suppression pathways.
• Tirzepatide: A dual-agonist that targets both the GLP-1 and GIP receptors. It is studied for its potential synergistic effects on metabolism and weight management models.

Choosing between them depends entirely on the specific receptor pathways your research aims to investigate.

Mechanism of Action & Primary Areas of Study

Semaglutide in Weight Loss Research Models

One of the most significant areas of study is the use of Semaglutide in weight loss models. Research focuses on its effects on the central nervous system to suppress appetite and its ability to delay gastric emptying. These studies help scientists understand the complex hormonal regulation of energy balance.

Glycemic Control Pathways

Semaglutide is a standard compound for investigating insulin secretion from pancreatic beta-cells and the suppression of glucagon. Its glucose-dependent mechanism of action makes it a key tool for creating and studying models of metabolic disorders.

Research-Grade vs. Compounded Semaglutide

It is critical for researchers to understand the distinction. "Compounded Semaglutide" is prepared by pharmacies, often for specific applications, and may contain different salt forms or excipients. In contrast, the research-grade Semaglutide from Peptides Skin is a pure, raw material (>99% purity) with a verifiable Certificate of Analysis. It provides a clean, consistent baseline for reproducible scientific experiments.

Technical Specifications

For precise calculations of your research solution, use our free Semaglutide Dosage Calculator.